Neuropathic Pain Facts and Solutions

Spinal Cord Stimulation

Sunday, May 10th, 2009

Many people with the following conditions have received tremendous pain relief from Spinal Cord Stimulation:

Failed Back and Neck Surgery

Cervical, Thoracic and Lumbar Radiculopathy

Reflex Sympathetic Dystrophy (RSD)

Complex Regional Pain Syndrome

Peripheral Neuropathy Pain

Phantom Limb Pain

Post-Herpetic Neuralgia

Other nerve-related pain syndromes

Spinal Cord Stimulation (SCS) is a safe and effective treatment method for various pain syndromes. In order for you to perceive pain, an electrical pain signal must travel from the origin of pain to your brain. The spinal cord stimulator delivers an array of electrical stimulation that blocks these pain signals. It replaces them with a pleasant tingling sensation referred to as a paresthesia.

When discussing SCS with patients, I use the analogy of dropping a hammer on your toe. There is an obvious source (the hammer) and location (your toe). The pain signal travels up nerves in the foot and leg to the spinal cord. It then travels up the spinal cord into the brain. At that point, you perceive the pain. One instinct is to rub your foot or ankle (not the toe). This rubbing creates an alternate signal that confuses your nervous system. This reduces the amount of pain signals transmitted to your brain. The SCS device delivers an electrical stimulus (a.k.a. the rubbing) directly over the area in the spinal cord where the pain signal is traveling. It prevents your brain from perceiving the full pain signal.

A SCS trial consists of placing one or two catheters into the epidural space utilizing X-Ray guidance.  No incisions are needed for this.  Each catheter contains between 4 and 8 electrical contacts.  The catheters are connected to an external battery.  The device is programmed to provide comfortable coverage of painful areas.  The patient can turn the device on/off, up/down, and change programs during the trial with a remote control.  If greater than 50% of pain relief is achieved with significant functional improvement, the trial is considered successful.  If we are both in agreement that this device will provide a significant improvement in quality of life, permanent SCS implantation is then scheduled.  I perform these on an outpatient basis under moderate sedation and local anesthesia (not general anesthesia).   On average, a trial takes 20-30 minutes and a permanent implant takes 75-90 minutes.

As an example, I recently performed a SCS trial for a patient who had 4 previous lumbar spine surgeries with continued low back and leg pain.  After conservative management was exhausted,  a two-lead SCS trial was performed 2 weeks ago.  During the trial, my patient reported 80% pain reduction.  As she enjoys gardening, she spent the entire week doing yard work that she has not been able to perform for years.  She stated that it was the first time in years that she woke up in the morning with no pain.  Permanent implantation is scheduled.

It is very important to realize that not everyone will benefit from a SCS device.  Success begins with proper patient selection.

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Peripheral Neuropathy

Tuesday, February 24th, 2009

Peripheral neuropathy is a common cause of chronic pain.  Causes of peripheral nerve damage include diabetes, autoimmune disorders, nutritional deficiencies, alcohol abuse, inherited diseases, and toxic drug exposure.  Approximately 15% of diabetics experience some form of peripheral neuropathy.

Initially, patients develop numbness and/or weakness in the hands or feet.  Early on, this involves the fingers and toes, but can work its way up the limbs.  Patients experience burning pain in the extremities – most commonly involving the feet.

Treatment is centered on the underlying disease.  Pain therapy involves medication management centered on neuropathic pain medications. In some cases, Spinal Cord Stimulation can be an effective long-term therapy.

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Neuropathic Pain Medications

Tuesday, February 24th, 2009

The treatment of neuropathic pain can be very difficult.  It is often necessary to conduct trials of multiple medications before finding the best regimen.  It is important to be patient as effective medications for one individual may be different than others.   These medications include:

Anti-epileptic (anti-seizure) medication – gabapentin, pregabalin, carbamazapine, etc.

Antidepressant medication  - tricyclics (e.g. amitriptyline), SSRIs (e.g. duloxetine)

Topicals – Local anesthetic preparations (creams, gels, patches), other compounded creams

Opiates

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